Set out your cream cheese to soften while you prep your jalapenos. Slice the jalapenos lengthwise, and remove the seeds. DO NOT slice the tops off of the jalapenos unless you like to clean an air fryer that's covered in melted cream cheese. If you want more mild stuffed jalapenos, you can also get in with a knife and carefully trim away the white or light green veins inside of the peppers.
In a small bowl, mix together the cream cheese and bacon bits.
Stuff about a tablespoon of the cream cheese mixture into each jalapeno half.
Pour the panko into a shallow bowl, and dip the cream cheese side of each jalapeno half into the panko. You want the panko to stick to the cream cheese, coating it well.
Arrange the jalapeno halves in your air fryer basket. Cook at 390° F for 10 minutes, then let them cool in the basket for 5 minutes before serving. The cream cheese will be very soft at this point, so use a wooden or rubber (NOT METAL) spatula to carefully scoop each one out. It is normal for them to stick together a bit. Gently pry apart any stuck-together jalapenos before lifting out of the basket.